MFAT vs. BMAC: Mesenchymal Stem Cell Therapy Showdown for Osteoarthritis Treatment

Author: Atkinson
Year: 2019

Review of “Functional Outcomes Following Microfragmented Adipose Tissue Versus Bone Marrow Aspirate Concentrate Injections for Symptomatic Knee Osteoarthritis” from STEM CELLS Translational Medicine by Stuart P. Atkinson

Osteoarthritis, a chronic degenerative disease of the articular cartilage, currently affects an estimated 30 million U.S. adults and costs over $185 billion a year to treat [1]; however, conventional conservative interventions often lack the ability to prevent the progression of osteoarthritis or providing long‐term improvements in pain and function [2]. Recent advances in treatments for osteoarthritis include therapies based on mesenchymal stem cells (MSCs) derived from the bone marrow or adipose tissue; but while both studies and clinical trials have provided evidence of the safety of said strategies [3, 4], we still require further data and well‐conducted trials to confirm their therapeutic utility.

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